Interpandemic Influenza A ( H 3 N 2 ) in Humans Epochal
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منابع مشابه
Epochal evolution shapes the phylodynamics of interpandemic influenza A (H3N2) in humans.
Human influenza A (subtype H3N2) is characterized genetically by the limited standing diversity of its hemagglutinin and antigenically by clusters that emerge and replace each other within 2 to 8 years. By introducing an epidemiological model that allows for differences between the genetic and antigenic properties of the virus's hemagglutinin, we show that these patterns can arise from cluster-...
متن کاملKatia Koelle , Interpandemic Influenza A ( H 3 N 2 ) in Humans Epochal
. clicking here colleagues, clients, or customers by , you can order high-quality copies for your If you wish to distribute this article to others . here following the guidelines can be obtained by Permission to republish or repurpose articles or portions of articles (this information is current as of September 30, 2010 ): The following resources related to this article are available online at ...
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A key priority in infectious disease research is to understand the ecological and evolutionary drivers of viral diseases from data on disease incidence as well as viral genetic and antigenic variation. We propose using a simulation-based, Bayesian method known as Approximate Bayesian Computation (ABC) to fit and assess phylodynamic models that simulate pathogen evolution and ecology against sum...
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